SARC awarded the following investigators and projects SARC Developmental Research Grants. A component of the SARC Sarcoma SPORE was funding for developmental research projects (2012–2016).

Funded Projects 2015–2016

DAVID KIRSCH, MD, PHD

YVONNE MOWERY, MD, PHD

Duke University Medical Center
Mechanisms that Regulate Sarcoma Response to Immune Checkpoint Inhibition of PD1

TSZ KWONG “CHRIS” MAN, PHD

Baylor College of Medicine
The Metastatic Role of Lysyl Oxidase in Osteosarcoma

WILLIAM W. TSENG, MD

University of Southern California
Immune Profiling in Well Differentiated/Dedifferentiated Liposarcoma

Funded Projects 2014–2015

LAURENCE BAKER, DO

University of Michigan
Can heart disease be predicted in young survivors of osteosarcoma using morphomics and/or coronary artery calcium scores?

DAVID KIRSCH, MD, PHD

YVONNE MOWERY, MD, PHD

Duke University Medical Center
Mechanisms that regulate sarcoma response to immune checkpoint Inhibition of PD1

SETH POLLACK, MD

Fred Hutchinson Cancer Research Center
Designing improved T-cell therapies for sarcoma patients

BRIAN RUBIN, MD, PHD

Cleveland Clinic Foundation
Identification of prognostic and therapeutic biomarkers in epithelioid hemangioendothelioma

ANAND SINGH, MD

Massaschusetts General Hospital
Computer-aided estimation of tumor viability fractions on MRI to facilitate procurement of negative surgical resection margins of musculoskeletal sarcoma

Funded Projects 2013–2014

ZHENFENG DUAN, PHD

Massachusetts General Hospital
Dissecting CDK11 kinase pathway in osteosarcoma

JONATHAN FLETCHER, MD

ADRIÁN MARIÑO-ENRIQUEZ, MD, PHD

Brigham & Women’s Hospital
Biomarkers for Dystrophin-deficiency in sarcoma

CHARLES KELLER, MD

Oregon Health & Science University

DAVID LANGENAU, PHD

Massachusetts General Hospital
GSK3-beta inhibitors for relapsed rhabdomyosarcom

DAVID KIRSCH, MD, PHD

REBECCA DODD, PHD

Duke University Medical Center
Translating discoveries from a mouse model into metastatic biomarker

STEPHEN LESSNICK, MD, PHD

SUNIL SHARMA, MD

University of Utah Huntsman Cancer Institute
Epigenetic targeting of LSD1 as a therapeutic strategy for Ewing sarcoma

BRIAN RUBIN, MD, PHD

Cleveland Clinic Foundation
Identification of prognostic and therapeutic biomarkers in epithelioid hemangioendothelioma

Funded Projects 2012–2013

ZHENFENG DUAN, PHD

Massachusetts General Hospital
Dissecting CDK11 kinase pathway in osteosarcoma

JONATHAN FLETCHER, MD

ADRIÁN MARIÑO-ENRIQUEZ, MD, PHD

Brigham & Women’s Hospital
Biomarkers for Dystrophin-deficiency in sarcoma

CHARLES KELLER, MD

Oregon Health & Science University

DAVID LANGENAU, PHD

Massachusetts General Hospital
GSK3-beta inhibitors for relapsed rhabdomyosarcoma

DAVID KIRSCH, MD, PHD

REBECCA DODD, PHD

Duke University Medical Center
Translating discoveries from a mouse model into metastatic biomarkers

STEPHEN LESSNICK, MD, PHD

SUNIL SHARMA, MD

University of Utah Huntsman Cancer Center
Epigenetic targeting of LSD1 as a therapeutic strategy for Ewing sarcoma

KEBIN LIU, PHD

Georgia Regents University

RAPHAEL POLLOCK, MD, PHD

Ohio State University
Combined radiosensitization and T cell immunotherapy for metastatic sarcoma

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