SARC ACTIVE Clinical Trials

Phase II Trial of bezuclastinib in combination with sunitinib in patients with GIST who progressed on sunitinib monotherapy.

TYPE OF SARCOMA: Gastrointestinal stromal tumor (GIST)
DRUG: Bezuclastinib in combination with sunitinib

ACCRUAL STATUS: Now recruiting for patients

Phase 3 Randomized Double-Blind Study of Abemaciclib Versus Placebo in Patients With Advanced Dedifferentiated Liposarcoma

TYPE OF SARCOMA: Advanced Dedifferentiated Liposarcoma
DRUG: Abemaciclib

ACCRUAL STATUS: Not recruiting

Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma

TYPE OF SARCOMA: Osteosarcoma
DRUG: Regorafenib, Nivolumab

ACCRUAL STATUS: Not recruiting

A Phase I/II Study to Evaluate the Safety of Trabectedin Administered as a 1-Hour infusion in Ewing Sarcoma Patients in Combination with Low Dose Irinotecan and 3’-Deoxy-3’-18F Fluorothymidine (18F-FLT) Imaging

TYPE OF SARCOMA: Ewing Sarcoma
DRUG: Trabectedin and Irinotecan

ACCRUAL STATUS: Not Recruiting

A Phase II Randomized Controlled Trial of Neoadjuvant Pembrolizumab With Radiotherapy and Adjuvant Pembrolizumab in Patients With High-Risk, Localized Soft Tissue Sarcoma of the Extremity

TYPE OF SARCOMA: Soft Tissue Sarcoma of the Extremity
DRUG: Pembrolizumab

ACCRUAL STATUS: Not recruiting