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Hosted by SARC’s Chief Medical Officer, Dr. Scott Okuno, alongside a rotating guest host, SARC Talk: Journal Club explores the latest advances in sarcoma research through engaging discussions of recently published studies, emerging scientific discoveries, and their potential impact on patient care. Each episode features expert perspectives that help clinicians, researchers, patients, and advocates stay informed on the evolving landscape of sarcoma science.
In this episode of SARC Talk Journal Club, we review the recent Lancet Oncology phase II trial evaluating the combination of cabozantinib and temozolomide in patients with unresectable or metastatic leiomyosarcoma and other soft tissue sarcomas. Our panel examines the study design, efficacy, safety profile, and clinical implications, discussing whether this combination represents a promising new treatment option and what questions remain for future research.
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