Home » Research » SARC ACTIVE Clinical Trials
Every day, our community of researchers, investigators, scientists, sarcoma centers, and biotech and pharmaceutical companies are working together in the development and support of clinical trials (studies). A list of SARC trials is provided here with a brief description and patient accrual status. Additionally, the National Institutes of Health provides an online registry and results database of clinical studies conducted around the world.
Phase II Trial of bezuclastinib in combination with sunitinib in patients with GIST who progressed on sunitinib monotherapy.
TYPE OF SARCOMA: Gastrointestinal stromal tumor (GIST)DRUG: Bezuclastinib in combination with sunitinib
ACCRUAL STATUS: Now recruiting for patients
Phase 3 Randomized Double-Blind Study of Abemaciclib Versus Placebo in Patients With Advanced Dedifferentiated Liposarcoma
TYPE OF SARCOMA: Advanced Dedifferentiated LiposarcomaDRUG: Abemaciclib
ACCRUAL STATUS: Not recruiting
Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma
TYPE OF SARCOMA: OsteosarcomaDRUG: Regorafenib, Nivolumab
A Phase I/II Study to Evaluate the Safety of Trabectedin Administered as a 1-Hour infusion in Ewing Sarcoma Patients in Combination with Low Dose Irinotecan and 3’-Deoxy-3’-18F Fluorothymidine (18F-FLT) Imaging
TYPE OF SARCOMA: Ewing SarcomaDRUG: Trabectedin and Irinotecan
ACCRUAL STATUS: Not Recruiting
A Phase II Randomized Controlled Trial of Neoadjuvant Pembrolizumab With Radiotherapy and Adjuvant Pembrolizumab in Patients With High-Risk, Localized Soft Tissue Sarcoma of the Extremity
TYPE OF SARCOMA: Soft Tissue Sarcoma of the ExtremityDRUG: Pembrolizumab